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Published Online
on September 4, 2008

Stroke. 2008
Published online before print September 4, 2008, doi: 10.1161/STROKEAHA.108.519306
A more recent version of this article appeared on December 1, 2008
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Submitted on March 5, 2008
Accepted on April 10, 2008

Deriving Modified Rankin Scores From Medical Case-Records

Terence J. Quinn MRCP*; Gautamananda Ray MRCP; Sari Atula MD; Matthew R. Walters MD; Jesse Dawson MRCP; and Kennedy R. Lees MD

From the Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

* To whom correspondence should be addressed. E-mail: Tjq1t{at}clinmed.gla.ac.uk.

Background and Purpose—Modified Rankin score (mRS) is traditionally graded using a face-to-face or telephone interview. Certain stroke assessment scales can be derived from a review of a patient's case-record alone. We hypothesized that mRS could be successfully derived from the narrative within patient case-records.

Methods—Sequential patients attending our cerebrovascular outpatient clinic were included. Two independent, blinded clinicians, trained in mRS, assessed case-records to derive mRS. They scored "certainty" of their grading on a 5-point Likert scale. Agreement between derived and traditional face-to-face mRS was calculated using attribute agreement analysis.

Results—Fifty patients with a range of disabilities were included. Case-record appraisers were poor at deriving mRS (k=0.34 against standard). Derived mRS grades showed poor agreement between observers (k=0.33). There was no relationship between certainty of derived mRS and proportion of correct grades (P=0.727).

Conclusion—Accurate mRS cannot be derived from standard hospital records. Direct mRS interview is still required for clinical trials.


Key words: clinical trials • drug trials • methodology • outcomes • randomized, controlled trials • scales • therapy • treatment




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