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Published Online
on August 14, 2008

Stroke. 2008
Published online before print August 14, 2008, doi: 10.1161/STROKEAHA.108.521062
A more recent version of this article appeared on November 1, 2008
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Submitted on March 25, 2008
Accepted on April 17, 2008

Quality of Ischemic Stroke Care in Emerging Countries. The Argentinian National Stroke Registry (ReNACer)

Luciano A. Sposato MD, MBA*; María M. Esnaola MD; Rafael Zamora MD; María C. Zurrú MD; Osvaldo Fustinoni MD; Gustavo Saposnik MD, MSc, FAHA; on behalf of ReNACer Investigators and the Argentinian Neurological Society

From the Stroke Center (L.A.S.), Neurosciences Institute at Favaloro Foundation, Buenos Aires, Argentina; the Stroke Unit, Department of Neurology (M.M.E.), Hospital Francés, Buenos Aires, Argentina; Hospital de Clínicas "José de San Martín" (R.Z.), Buenos Aires, Argentina; the Stroke Center, Department of Neurology (M.C.Z.), Hospital Italiano, Buenos Aires, Argentina; Cerebrovascular Diseases, Department of Neurology (O.F.), INEBA - Instituto de Neurociencias Buenos Aires, Buenos Aires, Argentina; St, Michael's Hospital, Division of Neurology, Department of Medicine and Health Policy Management and Evaluation (G.S.), University of Toronto, and Stroke Outcome Research in Canada (SORCan) Working Group (G.S.), Toronto, Canada.

* To whom correspondence should be addressed. E-mail: lucianosposato{at}gmail.com.

Background and Purpose—Limited information is available on stroke management in developing countries. An accurate monitoring of quality of stroke care will become crucial, particularly with the emerging paradigm of pay-for-performance. Our aim was to explore the feasibility of measuring standardized indicators of quality of ischemic stroke care in acute care facilities in Argentina.

Methods—ReNACer is a prospective, multicenter, countrywide, stroke registry comprising 74 academic and nonacademic institutions in Argentina. The registry includes patient-level information on demography, clinical characteristics, diagnostic procedures, treatment, and the selected key performance indicators of quality of ischemic stroke care (access to thrombolysis or aspirin use in the acute setting, admission to designated stroke units, length of stay, risk-adjusted in-hospital pneumonia, risk-adjusted in-hospital mortality, discharge on antithrombotics, and antihypertensive agents).

Results—We included 1991 patients with ischemic stroke from 74 institutions in Argentina between November 2004 and October 2006. Seventy-nine per cent of the patients were prescribed antithrombotic therapy within 48 hours of admission, but only 1% received thrombolytics. No more than 5.7% were admitted to stroke units. In-hospital pneumonia was diagnosed in 14.3% of the patients and was higher in nonacademic facilities (16.4% versus 11.4%, P<0.02). The overall adjusted in-hospital mortality was 9.1%, also higher in nonacademic hospitals (10.6% versus 7.1%, P<0.008). At discharge, antithrombotics were prescribed in 90.2% and antihypertensive agents in 63.6% of the patients.

Conclusions—In ReNACer, there was a limited access to stroke units and thrombolytics, and a relatively high incidence of in-hospital pneumonia. Differences in stroke care were observed between academic and nonacademic institutions. There is an urgent need to develop national stroke programs in Argentina.


Key words: stroke • quality of care • health policy • stroke outcome • health services research • thrombolytic therapy • health indicators • antithrombotics • hypertension • mortality




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Advances in Health Policy and Outcomes
Stroke, May 1, 2009; 40(5): e301 - e304.
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