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Published Online
on January 29, 2009

Stroke. 2009
Published online before print January 29, 2009, doi: 10.1161/STROKEAHA.108.532416
A more recent version of this article appeared on May 1, 2009
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Right arrow Angioplasty and Stenting

Submitted on July 23, 2008
Accepted on August 28, 2008

Would Self-Expanding Stent Occlude Middle Cerebral Artery Perforators?

Thomas W. Leung MRCP*; Simon C.H. Yu FRCR; Wynnie W.M. Lam FRCR; Anne Y.Y. Chan MRCP; Alexander Y.L. Lau MRCP; and Lawrence K.S. Wong MD

From the Division of Neurology, Department of Medicine and Therapeutics (T.W.L., A.Y.Y.C., A.Y.L.L., L.K.S.W.), and the Department of Radiology and Organ Imaging (S.C.H.Y., W.W.M.L.), Prince of Wales Hospital, The Chinese University of Hong Kong.

* To whom correspondence should be addressed. E-mail: drtleung{at}cuhk.edu.hk.

Background and Purpose—A major concern of intracranial stenting is perforator infarction. It is unclear whether the sustained radial force of a self-expanding stent or subsequent stent restenosis would cause late occlusion of perforators.

Methods—We compared the baseline and poststent (≥4 months) MRI scans of patients who underwent self-expanding stenting for recurrent ischemic symptoms attributed to a MCA stenosis ≥60%. New infarcts in the ipsilateral striatocapsular region were recorded.

Results—MCA stenting was technically successful in 23 of 24 recruited patients. No new perforator territory infarct was found in follow-up MRI scans of all recruited patients. Postoperatively, all patients reported no further TIA or stroke over a median follow-up of 15 months.

Conclusions—The use of a self-expanding stent in patients with high-grade MCA stenosis may not pose a major risk to the perforators.


Key words: intracranial stenosis • angioplasty • stenting • perforator territory infarction