The Effect of Isordil and Cyclospasmol on Vascular Spasm Induced in the Basilar Artery of the Cat
Vasospasm of the basilar artery of the cat was induced by subarachnoid bleeding and was observed by a transoral approach to the vessel. Intravenous Isordil (2 to 4 mg/kg) given following vasospasm produced vasodilatation with minimal arterial hypotension. Cyclospasmol, administered intravenously after vasospasm or orally prior to vasospasm, was ineffective in relieving or preventing basilar artery spasm.
- © 1970 American Heart Association, Inc.