Antifibrinolytic Activity During Administration of Epsilon-Aminocaproic Acid
Utilizing an in vitro method for activated and nonactivated whole blood clotlysis determinations, the antifibrinolytic effect of epsilon-aminocaproic acid therapy was evaluated. Initially, the induced antifibrinolytic activity diminished within two hours after the previous dose. Continuing therapy for three to six days resulted in sustained fibrinolytic inhibition.
- © 1971 American Heart Association, Inc.