Background and Purpose The aim was to determine whether a delayed transfer to an enriched environment improves outcome after focal brain ischemia.
Methods Performance on a rotating pole, prehensile traction, limb placement, and postural reflexes were tested in 15 spontaneously hypertensive rats housed in standard laboratory cages for 2 weeks after middle cerebral artery ligation. Seven of the 15 rats were then transferred to an enriched environment, and the two groups were tested 1, 3, and 5 weeks later.
Results The enriched environment significantly improved pole performance, prehensile traction, and limb placement.
Conclusions Delayed postoperative environmental enrichment improves outcome in experimental stroke.
- Received July 3, 1995.
- Revision received September 22, 1995.
- Accepted October 23, 1995.
- Copyright © 1996 by American Heart Association