Role of Estrogen and Endothelium in Migraine in Young Women
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To the Editor:
We read with great interest the recent article by Tietjen and colleagues1 dealing with migraine and endothelial activation in young women. The results of their study demonstrated a strong relation between migraine and endothelium-related biomarkers, including von Willebrand factor activity, high-sensitivity C-reactive protein, and total nitrite/nitrate concentration, in a young, relatively healthy cohort of women. The authors suggest that, in premenopausal women with migraine, there is evidence …