Abstract WP141: The Role Of Paroxysmal Atrial Fibrillation In Patients With Retinal Artery Occlusion (rao)
Background: Patients with retinal artery occlusion (RAO) have a 2.0 fold increase in risk for subsequent stroke and share similar risk factors with stroke patients. The pathophysiologic role of atrial fibrillation (AF), especially in its paroxysmal presentation, is poorly understood. We hypothesized that AF is similarly prevalent in RAO as in ischemic stroke (IS).
Materials and methods: In the Find-AF-eye trial, 50 patients with RAO were subsequently recruited into a prospective cohort study. 49 patients with venous retinal thrombosis (VRT) and 280 patients with ischemic stroke (IS) served as controls. Comprehensive evaluation included carotid artery Duplex examination, 7-day Holter ECG, transthoracal and transesophageal echocardiography and assessment of lipid and glucose status. AF was defined as an atrial arrhythmia for at least 30 seconds.
Results: 6 RAO patients (12.0 %), 5 VRT patients (10.2 %) and 48 IS (17.1 %) patients had a history of AF or had AF in the admission ECG. During 7-day Holter, 34 additional patients were diagnosed to have paroxysmal AF during 7-day Holter (2 RAO, 4 VRT, 28 IS patients). The overall prevalence of any AF was not significantly different between RAO (16.0 %) and VRT (18.3 %), p=0.79, but tended to be higher in IS (27.1 %), p=0.109 vs. RAO and p=0.195 vs. VRT.
Conclusion: Our data do not support a relevant pathophysiologic role of AF in patients with RAO.
- © 2012 by American Heart Association, Inc.