Abstract WP319: Can Acupuncture Benefit Putaminal Hemorrhagic Stroke Patients? A Randomized Controlled Clinical Trial.
Background: Acupuncture is a low-risk treatment with purported claims of effectiveness for poststroke rehabilitation. Poor study quality hinders the strength of previous studies to support acupuncture as a routine clinical practice. Moreover, most of the reported studies focus on ischemic stroke patients. In daily neurosurgical encounter, putaminal hemorrhagic stroke patients have a significantly worse functional and neurological prognosis than ischemic stroke patients.
Hypothesis: We hypothesize that acupuncture can improve functional outcome of putaminal hemorrhagic stroke patients by improving the neurological outcome.
Study design: Randomized controlled clinical trial (ClinicalTrial.gov: NCT01037894).
Study population: Putaminal hemorrhagic stroke patients who are hemiplegic and can cooperate with acupuncture treatment.
Study intervention: Acupuncture treatment for six weeks versus placebo. All patients received intensive inpatient rehabilitation.
Study outcome: Functional (primary) outcome is measured by Functional Independent Measure (FIM); Neurological (secondary) outcomes include by Fugl-Meyers Scale (FMS), Modified Functional Ambulation Category (MFAC), Modified Rivermead Mobility Index (MRMI), Glasgow Outcome Scale Extended (GOSE), Neurocognitive State Examination (NCSE), and Short Form-36.
Results: Twenty-nine eligible patients were randomized and completed all assessments. Acupuncture and placebo groups have similar baseline FIM scores (p=0.337). At both weeks 3 and 6 assessments, the FIM scores are significantly higher among acupuncture group (week 3: 51+/-19 vs 68+/-20, p=0.027; week 6: 59+/-20 vs 80+/-23, p=0.017). There is also significant improvement of FMS of lower limbs at week 6 but not upper limbs.
Conclusions: Acupuncture, in addition to intensive inpatient rehabilitation, improves functional and neurological outcomes of putaminal hemorrhagic stroke patients. Rehabilitation of the upper limb function remained a challenge for putaminal hemorrhagic stroke patients.
- © 2012 by American Heart Association, Inc.