In the article by Al-Ali et al, “Capillary Index Score in the Interventional Management of Stroke Trials I and II,” which published online ahead-of-print on May 22, 2014, and appears in the July issue of the journal (Stroke. 2014;45:1999–2003), corrections were needed.
Figures 2 and 3 were replaced together with their legends.
Figure 2 legend read: Theoretical relationship between good outcomes and time. The 50% barrier is caused by a decline in residual cerebral blood flow so steep that early treatment cannot reverse tissue damage. Group 1 denotes patients rarely enrolled in studies because of early signs of irreversible ischemia; Group 2 denotes patient population in most intra-arterial treatment for acute ischemic stroke trials; Group 3 denotes patients excluded from most studies because of artificial time window. MCA indicates middle cerebral artery.
Figure 2 now reads:
Outcome versus time. Theoretical relationship between good outcomes and
time. The 50% barrier is caused by a decline in residual cerebral blood flow so steep that ~50% of patients cannot be treated fast enough to prevent irreversible ischemia (due to lack of sufficient collaterals). Time to treatment is irrelevant for these patients. MCA indicates middle cerebral artery.
Figure 3 legend read:
Logarithmic time curve: infarction threshold distinguishing
between reversible and irreversible ischemia as a function of
residual cerebral blood flow (rCBF) and time from ictus. The vertical
lines are an approximation and have not yet been validated.
Figure 3 now reads:
The logarithmic relationship between time to irreversible ischemia and residual cerebral blood flow (rCBF). The overall relationship between time from ictus and irreversible ischemia is not a linear but rather a logarithmic one. The curve consists of three sections, each corresponding to a group of patients. Group I patients experience early irreversible ischemia (50% barrier) and are rarely enrolled in IAT-AIS studies. Group 2 are those in most trials. Those in Group 3 are excluded from most studies due to an artificial time window. MCA indicates middle cerebral artery. Adapted from Jones et al6 with permission from the publisher. Copyright © 1981, American Association of Neurological Surgeons. Authorization for this adaptation has been obtained both from the owner of the copyright in the original work and from the owner of copyright in the translation or adaptation.
The authors apologize for this error.
These corrections have been made to the online and print version of the article.
- © 2014 American Heart Association, Inc.