Abstract T MP82: Time to Recanalization after Cerebral Venous Thrombosis
Background and Purpose: Cerebral venous thrombosis (CVT) comprises around 0.5% of strokes. Early initiation of anticoagulants, is safe and ensues a better functional prognosis. Different studies have addressed the issue, the rate and moment of recanalization has not been sufficiently defined, and it may have relevancy regarding treatment decisions. Our purpose was to estimate the time to recanalization of adults with acute CVT at one year follow-up.
Methods: We prospectively studied a group of patients with confirmed diagnoses of CVT. Neuroimaging and clinical follow-up were performed at 3, 6, 9 and 12 months. All patients were treated with oral anticoagulant for 12 months or until complete recanalization. Statistical analysis used Kaplan-Meier method for survival tables.
Results: We included 101 patients; median age was 33.6+11, women 79 (78.2%); 99 (98.0%) were evaluated and follow-up with MR venography. Complete recanalization at one year was accomplished in 65 (64.4%), partial in 29 (28.7%) and no recanalization in 7 (6.9%). We found that the proportion of any recanalization at 3 months was 65.3±4.7%, 6 months 89.1±3.1%, 9 months 91.5%±2.8% and 12 months 93.9%±6.1%. Complete recanalization at 3 months was 27.7±4.5%, 6 months 55.6±5.0%, 9 months 63.2%±5.0% and 12 months 68.5%±4.9%.
Conclusions: Our result displays that at least partial recanalization in CVT occurs mainly within the first 6 months. However, there is a significant proportion of patients that achieve complete recanalization until 9 months of treatment regardless of the site of occlusion.
Author Disclosures: N. Arguelles-Morales: None. J. Vargas-Gonzalez: None. A. Ruiz-Franco: None. A. Quiroz-Compean: None. A. Arauz-Gongora: None.
- © 2014 by American Heart Association, Inc.