Abstract T P175: Symptoms and Signs of Cerebrovascular Ischemia in the New England Medical Center Patent Foramen Ovale Registry
Objective: To evaluate the frequencies of symptoms and signs in patients with cryptogenic strokes in the setting of patent foramen ovale (PFO).
Methods: We conducted a retrospective case series of cryptogenic stroke patients at the NEW England Medical Center, with proven PFO. The patients' records were reviewed for: 1) Activity at time of symptoms, 2) symptoms, 3) physical exam finding.
Results: The study included 148 men (58%) and 109 women (42%). The average age was 52 years. The most frequent activity at the time of symptoms onset were lifting weights (30%), bending (34%), coughing/ sneezing/ nose blowing (16%), intercourse (7%), vomiting (5%). A history of prolonged immobility was present in 31% of patients. The most frequent presenting symptoms were unilateral weakness (46%), dysarthria (17%), unilateral numbness (11%), unsteady gait (10%), visual field defect (9%), diplopia (8%), vomiting (6%). The most frequent signs were normal exam (52%), unilateral weakness (14%), visual field deficits (13%), ataxia (4%), neglect/ inattention (2%), Babinski (3%), nystagmus (2%), unsteady gait (1%).
Conclusion: We report our experience with cryptogenic stroke in patients with proven PFO. The disparity in frequencies of the signs and symptoms at the time of presentation raises the possibility of including these variables in an algorithm for predicting PFO in the setting of cryptogenic stroke.
Author Disclosures: H. Toma: None. D.E. Thaler: Consultant/Advisory Board; Modest; Steering Committee, RESPECT Trial, St Jude Medical. Research Grant; Significant; NINDS.
- © 2014 by American Heart Association, Inc.