Abstract W MP103: Stroke Patients with Atrial Fibrillation Who Had Left Atrial Thrombus Are Likely to Have Increased Recurrence in the Long Term
Background and objective: This study retrospectively investigated long term recurrence rate in stroke patients with atrial fibrillation (AF) who had left atrial thrombus (LAT).
Methods: Participants compromised 359 consecutive stroke patients with AF less than 7 days after onset who had undergone transesophageal echocardiography. Patients were divided into LAT and non-LAT groups based on the presence or absence of LAT. Clinical background, neurological findings, imaging findings and stroke recurrence within 3 years of discharge were then compared between the two groups.
Results: Fifty-nine patients were classified into the LAT group and 300 patients into the non-LAT group. Median age of the LAT and non-LAT groups was 78 and 76 years, respectively (p=0.57), and the LAT group had a higher proportion of females (53% vs. 39%, p=0.06) and hypertension (81% vs. 69%, p=0.06). CHADS2 score was higher in the LAT group than in the non-LAT group (median score: 3 vs. 2; p<0.01). Median National Institute of Health Stroke Scale score for the LAT and non-LAT groups was 7 vs. 4 (p=0.05). The proportion of patients with a maximum cerebral infarction diameter ≥3 cm was also greater in the LAT group (61%) compared to the non-LAT group (37%; p=0.02). The recurrence rate (RR) during hospital stay was 3.4% vs. 7.3%, respectively (p=0.40). However, cumulative RR for the 3-year period after discharge was significantly higher in the LAT group (25%) than in the non-LAT group (12%; HR, 2.61; p=0.03; Fig.1).
Conclusion: Compared to patients without LAT, stroke patients with AF who previously had LAT are more likely to have increased recurrence in long term, but not in the short term.
Author Disclosures: S. Yamashita: None. N. Matsumoto: None. N. Saji: None. J. Uemura: None. K. Shibazaki: None. K. Kimura: None.
- © 2014 by American Heart Association, Inc.