Abstract T P186: The Effectiveness of the Motor Component of the National Institute of Health Stroke Scale at Predicting the Functional Outcome at Discharge in Patient Receiving Endovascular Therapy
Background and Purpose: The National Institute of Health (NIH) developed a standardized scale to evaluate the severity of a stroke at presentation. Predicting patient outcome after a vascular event can be very challenging. The objective of this analysis was to study the effect of the motor component of the NIH Stroke Scale (NIHSS) on a patient’s functional outcome at discharge looking at a multicenter group to further validate our observation.
Methods: This is a retrospective analysis of all patients (n= 161) that presented to the hospitals with ischemic stroke and received mechanical thrombectomy between January 2009 and July 2014 and had all the components of NIHSS baseline documented at presentation. Statistical analysis was performed using GraphPad Prism to independently evaluate the relationship between the NIHSS components and patient functional outcome at discharge using modified rankin scale (mRS). mRS of 2 or less represented a good functional outcome. All variables were included in the analysis.
Results: 112 patients that had all variables and their NIHSS breakdown components documented were included. Group analysis including gender, mean age, mean NIHSS, Afib%, DM%, Prior Stroke % and mortality at discharge were as follows: Female 52.7%, 72.1±16.3, 15.2±7.2, 34.8%, 27.7%, 25.9% and 12.5%. All Motor components of NIHSS in order left arm, left leg, right arm, right leg had a significant correlation with poor patient outcome at discharge (95%CI -3.932- -0.9607, P<0.001); (95%CI, -3.843- -0.8714, P<0.001); (95%CI, -3.584- -0.6125, P<0.01); (95%CI, -3.539- -0.5678, P<0.01). A higher motor score at presentation correlated with a worse outcome at discharge. NIHSS was significantly correlated with poor functional outcome (95% CI 9.881 -13.423 P<0.001).
Conclusion: Admission motor grade may serve as a good predictor of disability and mortality in patients undergoing mechanical thrombectomy with acute ischemic stroke. Further prospective study to validate such an observation is warranted.
Author Disclosures: H. Dababneh: None. H. Zheng: None. S. Sakian: None. K. Arcot: None. A. Bashir: None. A. Tiwari: None. S. Azhar: None. J. Farkas: None. M. Hussain: None.
- © 2015 by American Heart Association, Inc.