Abstract T P9: Procedural And Clinical Outcomes Of Intra-arterial Thrombectomy In Acute Ischemic Stroke Patients Over 75 Years Of Age
Background & objective: Age is an important factor related with favorable outcome after intraarterial thombectomy (IAT). However, procedural and clinical limitations of aging in IAT have not been well studied. We evaluated procedural and clinical outcomes of IAT observed in patients over 75 years as compared to the data of younger than 75 years.
Methods: We retrospectively reviewed procedural and clinical data of 50 patients older 75 years and other 127 patients younger than 75 years old, who received IAT using recently introduced retrievable stent and/or suction device. We compared procedural variables including groin puncture to selection of occluded vessel time, puncture to recanalization time, and recanalization rate. We also compared clinical variables including hemorrhagic complication, mortality, and rate of favorable outcome defined as 0 to 2 of modified Rankin scale at discharge and 3 months.
Results: Patients over 75 years old took longer time intervals from puncture to selection of occlusion sitethan the younger patients (>75, 12.1±10.3, <75 group, 5.9±4.8 min; p=0.000). The older patients showed lower number of patients recanalized within 6 hours than younger patients (23, 46% vs. 84 patients, 66%; p=0.011). Older patient group had lower rate ofrecanalization (60% vs. 79%; p=0.010) and favorable outcome at discharge (20% vs. 43.3%; p=0.003) and 3months (24% vs. 55.1%; p=0.000). Even though symptomatic hemorrhage was similar between the 2 groups, mortality was higher in older patient group (14% vs. 5%; p=0.062). In multiple logistic regression analysis, younger age less than 75 years (OR 3.1, 95% CI 1.18-8.04) and recanalization within 6 hours (OR 3.0, 95% CI 1.23-7.32) were independently related with a favorable 3-month outcome.
Conclusions: The present study showed that clinical and procedural outcomes of IAT performed for old age over 75 years were worse than those of younger patients. However, even in the older patients, successful recanalization and favorable outcome was also anticipated.
Author Disclosures: H. Jeong: None. H. Kwon: None. H. Song: None. H. Koh: None. J. Kim: None.
- © 2015 by American Heart Association, Inc.