Abstract W MP102: Development and Validation of a Short Form for the Stroke Impact Scale
Introduction: The Stroke Impact Scale (SIS) is an eight domain (59 item) stroke specific quality of life measure. A short form of SIS (SF-SIS) has been proposed but requires independent validation.
Methods: We used patient-level data contained in the Virtual International Stroke Trial Archive (VISTA). SIS was available for rehabilitation settings, a modified scale SIS-16 was predominantly used in acute settings. For both groups we extracted and standardised clinical and demographic data. We derived a short form index (SIS-VISTA) by selecting 8 items, one per domain; choosing those items most highly correlated with total domain score. Validation compared short forms with SIS/SIS-16 (Cronbach’s alpha) and other outcomes as available:Barthel Index; EQ-5D; visual analogue scale (VAS); mRS; NIHSS (correlation).
Results: Acute data comprised n=5549 (603 intracerebral haemorrhage [ICH]) mean age:68.5 (SD:13); mean SIS:64 (SD:32). SIS-VISTA items agreed with SF-SIS for all available domains other than communication. Results did not differ in analyses restricted to ICH. Rehabilitation data, n=332 (mean age 65.7 [SD:11]; mean SIS:61 [SD:11]) preferred SIS-VISTA items agreed with SF-SIS for all domains except communication, ADL and mobility. Where items did not match differences in correlation were minimal. Short forms demonstrated good agreement with SIS and correlation with other metrics of interest (table).
Conclusions: Using multiple approaches we have validated SIS short forms. There was no significant difference between existing SF-SIS and SIS-VISTA and we would encourage researchers to use SF-SIS to allow collection of robust quality of life data with less associated test burden.
Author Disclosures: R.L. Fulton: None. M. Ali: None. M. Peters: None. C. English: None. H. Rodgers: None. K.R. Lees: None. T.J. Quinn: None.
- © 2015 by American Heart Association, Inc.