Abstract W P120: Patterns of Vessel Involvement of Intracranial Stenosis in the Young
Introduction: Intracranial stenosis in the young has various etiologies. We sought to identify patterns of vessel involvement of intracranial stenosis.
Methods: This is a retrospective cohort study of young patients (≤50 years old) with intracranial stenosis seen in the stroke clinic of a tertiary center from 2008-2013. Patients were grouped by clinical diagnosis of 1. atherosclerosis (≥ 3 traditional risk factors ) 2. vasculitis ; 3. RCVS; 4. unknown etiology. Stenosis location and severity were compared among these groups based on cerebral angiography, CTA, or MRA.
Results: A total of 128 patients were identified in this cohort. Of this cohort, presumed atherosclerosis (56%) was the most common etiology followed by unknown etiology (21%). Distinct patterns of stenosis were noted among these categories (see table). Atherosclerosis was more commonly identified in the anterior circulation (68.1%, p=.036). Moyamoya disease and the vasculitides had high predilection for MCA stenosis. RCVS showed a more diffuse vessel involvement which includes posterior circulation.
Conclusion: Distinct of patterns of vessel involvement are seen among different etiologies of intracranial stenosis in the young. These patterns may help in determining the etiology of intracranial stenosis in this population.
Author Disclosures: J. Mathew: None. T. Strohm: None. R. Cerejo: None. I. Katzan: None. K. Uchino: None.
- © 2015 by American Heart Association, Inc.