Abstract W P13: Time To Recanalization With New Thrombectomy Devices In Intra-arterial Therapy For Acute Ischemic Stroke
Introduction: Faster time to recanalization is a strong predictor of good outcome after acute ischemic stroke (AIS) from large vessel occlusion (LVO). Intra-arterial therapy is an option for AIS from LVO, but studies have not shown benefit with this modality. This may be related to delayed recanalization time. We compared the speed of recanalization with newer devices
Methods: Retrospective study of patients who underwent IAT for AIS from 1/10 -6/14 at our institution was conducted. Data regarding baseline demographics, treatment times and thrombectomy devices were recorded for all patients who achieved successful recanalization defined as TICI2b-3. Comparisons were drawn between the patients who underwent IAT with the Penumbra aspiration system (Penumbra Inc, Alameda, CA), stent-trievers and direct aspiration (DA) with new large bore catheters such as 5 MAX and 5 MAX ACE (Penumbra Inc).
Results: 113 patients achieved successful recanalization. Penumbra aspiration was used in 48 (42.4%), stent-trievers in 37 (32.7%) and direct aspiration in 28 (24.7%) patients. Baseline demographics are detailed in the table and were non-significant between groups. Time from first run to recanalization was shortest in the DA group (49.5 ± 31.6 minutes), followed by Penumbra aspiration system (61.5 ± 39.8) and stent-trievers (71.6 ± 35.1). DA was significantly faster than Penumbra aspiration system (p 0.0354) and the stent-triever (0.0100).
Conclusion: Improvements in device technology and interventional technique allows for effective recanalization in significantly shorter times compared to previous methods. The impact of these developments will have to be tested in randomized controlled trials to assess its influence on outcomes
Author Disclosures: S. John: None. D. Wisco: None. K. Uchino: None. G. Toth: None. E. Cheng-Ching: None. S. Man: None. M.S. Hussain: None.
- © 2015 by American Heart Association, Inc.