Abstract W P132: Poststroke Depression After Intracerebral Hemorrhage At Young Age
Background and Purpose: Poststroke depression (PSD) is an important complication of stroke. We studied long-term PSD after intracerebral hemorrhage (ICH) at young age, as well as the quality of life of the survivors.
Methods: We gathered clinical and imaging data on young ICH patients between age 16 and 49 treated in the Helsinki University Central Hospital between January 2000 and March 2010. The survivors were interviewed with structural questionnaires including Beck Depression Inventory II (BDI-II), Hospital Anxiety and Depression Scale (HADS), EuroQol (EQ-5D), Pain Anxiety Symptoms Scale (PASS-20), Brief Pain Inventory (BPI), and Montreal Congnitive Assessment (MOCA). Univariate analysis was performed to identify baseline factors associated with PSD (BDI-II score > 13). Correlation between degree of disability measured by modified Rankin Scale score and PSD was analyzed.
Results: Median follow-up time was 9.7 [7.0-12.0] years. PSD was present among 30 (23.1%) out of 130 patients included. Mild or moderate emotional distress was present in 47 (36.2%) patients (HADS score > 7). Discomfort or pain was reported by 55 (42.3%) patients (measured by EQ-5D). Higher degree of disability was associated with symptoms of depression (higher BDI-II scores, p=0.001), and emotional distress (higher HADS scores, p=0.004). The only baseline factor identified to associate with PSD was hydrocephalus (p=0.014). Median PASS-20 score was 9 (IQR 0-25), median BPI score was 5 (0-23), and median MOCA score was 26 (22-28).
Conclusions: One out of four survivors of ICH at young age suffers long-term PSD. Higher degree of disability predicted occurrence of PSD.
Author Disclosures: R. Koivunen: None. T. Tatlisumak: None. J. Putaala: None.
- © 2015 by American Heart Association, Inc.