Abstract W P199: Time Needed To Find - A New Metric For Evaluating Screening Strategies For Atrial Fibrillation In Stroke Patients
Background: Numerous observational and two published multicenter randomized controlled studies have evaluated different screening strategies and modalities for finding undiagnosed atrial fibrillation (AF) in stroke. Usually, the number needed to screen (i. e. how many patients have to undergo a certain screening strategy to find one case of AF) has been used to describe the efficiency of a single screening strategies. However, screening is often confined to small subgroups (e. g. elderly patients, patients with cryptogenic stroke), but this is not accounted for in the number needed to screen.
Methods: We searched MEDLINE and available meta-analyses for multicenter observational and randomized trials that analysed screening strategies. We defined time needed to find (TNF) as the ratio of number needed to screen (NNS) to average recruitment rate per month and per study site. Only AF episodes lasting > 30 seconds were included into the analysis.
Results: Five trials fulfilled the inclusion criteria (3 randomised, 2 observational). Details on the trials and on NNS and TNF are shown in the table.
Conclusion: Time needed to find (TNF) is a new metric to describe how many patients can be found with different screening strategies in a single study center per month. We propose to use this parameter when evaluating diagnostic modalities and strategies for finding undiagnosed AF in stroke patients.
Author Disclosures: R. Wachter: None. M. Weber-Krüger: None. J. Liman: None. G.F. Hamann: None. S. Klimpe: None. P. Kermer: None. M. Grond: None. K. Gröschel: None.
- © 2015 by American Heart Association, Inc.