Letter by Du et al Regarding Article, “Magnetic Resonance Imaging of Plaque Morphology, Burden, and Distribution in Patients With Symptomatic Middle Cerebral Artery Stenosis”
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To the Editor:
The study by Dieleman et al1 recruited patients with symptomatic middle cerebral artery stenosis, revealed plaque morphological characteristics, and compared the features between symptomatic and asymptomatic lesions using a 3T vessel wall sequence. The authors found that eccentricity was associated with asymptomatic lesions, whereas there was no relationship between symptomatic lesions and any specific morphological features. With great interest, we have some opinions about the study.
First, this study is a lack of quantitative magnetic resonance imaging measurements (eg, lumen area, wall area, wall thickness, plaque burden rate, arterial remodeling rate, and luminal stenosis) that may minimize the operator dependence …