Response by Brinjikji to Letter Regarding Article “Neurons Over Nephrons: Systematic Review and Meta-Analysis of Contrast-Induced Nephropathy in Patients With Acute Stroke”
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We thank Malhotra et al for their interest in our Neurons over Nephrons study.1 As they pointed out, there were some limitations to the included studies. We attempted to control for these in our meta-regression and in our subgroup analysis of patients who presented with baseline chronic kidney disease. Both of these analyses showed no association between contrast administration and acute kidney injury. Although it is possible that we underestimated the rate of acute kidney injury because of …