Response by Lee and Ovbiagele to Letter Regarding Article, “Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis”
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We sincerely thank Professor Spence for his interest in our study1 on antiplatelet strategies for patients with breakthrough ischemic strokes while on aspirin and we agree with his comments in general. To his main comment, “if a patient has a stroke while on antiplatelet therapy it is crucial to consider why it happened,” we addressed this issue in the second sentence of our introduction, “Secondary prevention in these patients requires comprehensive management of vascular risk factors and detailed investigation of …