Response by Aigner et al to Letter Regarding Article, “Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults”
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We thank Dr Braillon for his comment on our study.1 It is a common problem in retrospective data analysis to be constrained to the use of data and variables previously collected for potentially other reasons than the study at hand. In our case–control study, an additional restriction was caused by the fact that data for cases and controls were derived from different data sources, which made harmonization of variables and definitions between these data sources necessary. Therefore, there was unfortunately no option of using physical activity or smoking behavior as continuous measures. However, both data sources were of high data quality; the GEDA study (German Health Update) as a nationwide representative health survey with standardized questionnaires, and the SIFAP …