Response by Bekelis et al to Letter Regarding Article, “Anesthesia Technique and Outcomes of Mechanical Thrombectomy in Patients With Acute Ischemic Stroke”
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We want to thank Drs Dexter and Hindman for their interest in our article.1 Our analysis has attempted to address the authors’ first concern. Clustering of observations in 1 particular hospital was addressed by using mixed effects methods with hospital identity as a random effects variable. Unmeasured confounding was addressed using an instrumental variable analysis. The regional rate of general anesthesia (hospital-level general anesthesia rate) was used as …