Response by Feldman et al to Letter Regarding Article, “Trends in Recruitment Rates for Acute Stroke Trials, 1990–2014”
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We thank Murray and Barrow for their response to our article, Trends in Recruitment Rates for Acute Stroke Trials, 1990–2014.1 We agree that one contributing factor to slow recruitment in acute stroke trials is the enhanced ability of Primary Stroke Centers to manage acute strokes and, in turn, the diminished need to transfer patients to regional academic medical centers where clinical trials are often based.
Expanding acute stroke trials to include more Primary Stroke Centers could increase the total number of patients screened by trial investigators and thereby bolster recruitment rates (participants per …