Letter by Freeman Regarding Article, “Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands)”
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To the Editor:
I read with great interest the article by Mulder et al1 on the blood pressure effect on MR CLEAN outcomes in acute stroke. The authors report a U-shaped mortality with systolic blood pressure (SBP), with an optimal SBP, or the bottom of the U being about 120 mm Hg. Either end of the U was associated with worse outcomes. The first question I ask is did the authors analyze whether …