Letter by O’Sullivan Regarding Article, “Neurons Over Nephrons: Systematic Review and Meta-Analysis of Contrast-Induced Nephropathy in Patients With Acute Stroke”
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To the Editor:
The findings of Brinjikji et al1 will be of great interest to the nephrology community and should prompt reflection on the challenges in understanding the association between contrast administration and AKI. Contrast-induced nephropathy is a surprisingly difficult entity to accurately diagnose in clinical practice, as healthy individuals rarely receive contrast, and patients who develop AKI around the time of contrast administration are rarely if ever biopsied. Thus, when clinicians observe a creatinine rise post–contrast administration, they must first overcome their own confirmation bias, …