Response by Johnson and Söderholm to Letter Regarding Article, “Serum Potassium Is Positively Associated With Stroke and Mortality in the Large, Population-Based Malmö Preventive Project Cohort”
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We thank Dr Spence for his interest in our article describing a positive association between serum potassium and stroke incidence and mortality in the MPP (Malmö Preventive Project) cohort,1and we are in agreement with him that serum potassium measures are influenced both by renal function and by medications that block the renin–angiotensin–aldosterone system.
In the article, we have made efforts to take renal function into account in the following ways. Our multivariable model includes serum creatinine as well as …