Letter by Liu et al Regarding Article, “Thrombolysis in Postoperative Stroke”
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To the Editor:
We have read with great interest the article by Voelkel et al1 investigating the safety of intravenous thrombolysis (IVT) in patients with postoperative stroke. The authors proposed that IVT may be administered safely in postoperative patients as off-label use after appropriate risk–benefit assessment. However, after a detailed analysis of this article, we have some opinions about the study, which need to communicate with the authors because the article directly relates to my clinical interest.
First, in results section, we noted that intracranial hemorrhage (ICH) occurred in 9.7% (13 of 134) and was asymptomatic in all cases. However, it is unclear when bleeding complications occurred after IVT in cases with postoperative stroke? If we knew the exact time, this might be meaningful because it …