Response by Voelkel and Hubert to Letter Regarding Article, “Thrombolysis in Postoperative Stroke”
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Thank you for your comments and helpful additions to our article Thrombolysis in Postoperative Stroke. First, you ask for notifying the exact time or onset of bleeding complications after intravenous thrombolysis (IVT) in postoperative stroke. The bleeding complications occurred immediately during or after IVT (ie, colon bleeding, hematoma expansion gluteal) or, regarding the intracranial hemorrhage (ICH), at least within 24 hours (ICH seen on the control computed tomographic scan on the following day). You comment that “asymptomatic ICH was not well defined” and that it “is not clear how asymptomtic ICH is evaluated.” As mentioned in our methods section, we used the definition following Safe Implementation of Thrombolysis-in-Stroke-Monitoring-Study criteria.1 ICH was defined as …