Stroke Literature Synopses: Clinical Science
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Historically, the cognitive consequences of stroke have received limited research attention. Yet, neuropsychological issues are common after stroke and stroke survivors consistently state that cognitive decline is their biggest concern. For this Clinical Synopsis, I have selected articles themed around vascular cognitive impairment (VCI). These articles are not trials—there have been depressingly few intervention trials in this field. Rather, I have chosen articles with a methodological flavor. I think, if we get the methods correct in VCI trials, then positive results will follow.
One of the fundamental barriers to progressing VCI research is that we have no agreed definition of the condition. Many classification systems are available but the content of each differs, and the resulting diagnoses can be contradictory. To try and bring some consistency, the VICCS group (Vascular Impairment of Cognition Classification Consensus Study) propose a novel VCI classification system. (Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, et al. The Vascular Impairment of Cognition Classification Consensus Study. Alzheimers Dement. 2017;13:624–633. doi: 10.1016/j.jalz.2016.10.007).
Rather than create a classification from scratch, the VICCS …