Cannabis Use, Ischemic Stroke, and Multifocal Intracranial Vasoconstriction
A Prospective Study in 48 Consecutive Young Patients
Background and Purpose—Our objective was to evaluate the relationship between cannabis use and ischemic stroke in a young adult population.
Methods—Forty-eight consecutive young patients admitted for acute ischemic stroke participated in the study. First-line screening was performed, including blood tests, cardiovascular investigations, and urine analysis for cannabinoids. If no etiology was found, 3D rotational angiography and cerebrospinal fluid analysis were performed. A control was planned through neurovascular imaging within 3 to 6 months.
Results—In this series, there was multifocal intracranial stenosis associated with cannabis use in 21% (n=10).
Conclusions—Multifocal angiopathy associated with cannabis consumption could be an important cause of ischemic stroke in young people.
- Received December 8, 2010.
- Accepted December 30, 2010.
- © 2011 American Heart Association, Inc.