The Level of Cortical Afferent Inhibition in Acute Stroke Correlates With Long-Term Functional Recovery in Humans
Background and Purpose—Using transcranial magnetic stimulation, we investigated short-interval intracortical inhibition and short-latency afferent inhibition in acute ischemic stroke.
Methods—We evaluated short-interval intracortical inhibition and short-latency afferent inhibition in the affected hemisphere and unaffected hemisphere in 16 patients and correlated electrophysiological parameters with outcome at 6 months.
Results—Affected hemisphere short-latency afferent inhibition was significantly reduced in patients, and short-latency afferent inhibition level correlated with functional outcome.
Conclusions—Reduced afferent inhibition in acute stroke correlates with long-term recovery.
- Received July 1, 2011.
- Accepted July 21, 2011.
- © 2011 American Heart Association, Inc.