Q&A with Dr. van den Berg
Stroke Progress and Innovation Awards 2015
Lucie A. van den Berg, MD
Lucie A. van den Berg, Diederik L.H. Koelman, Olvert A. Berkhemer, Anouk D. Rozeman, Puck S.S. Fransen, Debbie Beumer, Diederik W. Dippel, Aad van der Lugt, Robert J. van Oostenbrugge, Wim H. van Zwam, Patrick A. Brouwer, Sjoerd Jenniskens, Jelis Boiten, Geert A. Lycklama à Nijeholt, Jan Albert Vos, Wouter J. Schonewille, Charles B.L.M. Majoie, Yvo B.W.E.M. Roos, for the MR CLEAN pretrial study group
SPOTLIGHT: Q&A with Dr. van den Berg
What is the key take-away message from your article?
Patients who do not receive general anesthesia (GA) during intra-arterial treatment (IAT) for acute ischemic stroke (AIS) have a higher probability of good clinical outcome and do not have higher complication rates than patients who undergo GA. Local anesthesia, with the possible use of conscious sedation (CS), during IAT for AIS seems a good strategy if possible.
What prompted you and your co-authors to perform this study?
There is growing evidence that non-GA is as feasible as GA during IAT and that GA may be associated with a lower rate of successful recanalization and worse clinical outcome. Currently no consensus exists about the optimal anesthetic management. As it will become a widely accepted treatment strategy in the field of neurology, optimizing this treatment is essential.
What is innovative about this work? And what are its applications?
When published, it was the largest study so far studying anesthetic management during IAT for AIS. Furthermore, in contrast to earlier studies, we had a balanced baseline stroke severity, therefore minimizing the effect of stroke severity on outcome.
Tell us about the biggest challenge you came across while conducting this study.
Definitely the retrospective character of the study and collecting all the data from the 16 participating centers. However, all the participating centers were very helpful, with hard work of the team we managed to collect most of the essential information.
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