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Original Contributions

Efficacy and Tolerability of Donepezil in Vascular Dementia: Positive Results of a 24-Week, Multicenter, International, Randomized, Placebo-Controlled Clinical Trial

Editorial Comment—How to Treat Vascular Dementia?

Effects of a Perindopril-Based Blood Pressure–Lowering Regimen on Disability and Dependency in 6105 Patients With Cerebrovascular Disease: A Randomized Controlled Trial

Dipyridamole in Stroke Prevention: Effect of Dipyridamole on Blood Pressure

Ten-Year Prognosis of Stroke and Risk Factors for Death in a Japanese Community: The Hisayama Study

Editorial Comment—Trends in Stroke Mortality

Trends in the Incidence, Mortality, and Survival Rate of Cardiovascular Disease in a Japanese Community: The Hisayama Study

Vegetable and Fruit Intake and Stroke Mortality in the Hiroshima/Nagasaki Life Span Study

Long-Term Mortality and Recurrent Stroke Risk Among Chinese Stroke Patients With Predominant Intracranial Atherosclerosis

Comparison Between Measures of Atherosclerosis and Risk of Stroke: The Rotterdam Study

Editorial Comment—Vascular Thickness and Calcification as Markers of Atherosclerotic Burden

Risk Factors for Progression of Atherosclerosis Measured at Multiple Sites in the Arterial Tree: The Rotterdam Study

Left Ventricular Mass and Geometry and the Risk of Ischemic Stroke

Editorial Comment—Left Ventricular Hypertrophy: An Unseemly Risk Factor for Stroke?

Risk of Ischemic Stroke Associated With Functional Thrombin-Activatable Fibrinolysis Inhibitor Plasma Levels

Change in Perfusion in Acute Nondominant Hemisphere Stroke May Be Better Estimated by Tests of Hemispatial Neglect Than by the National Institutes of Health Stroke Scale

Editorial Comment—Measurement of Cognitive Deficits in Acute Stroke

Diabetic Patients Have an Impaired Cerebral Vasodilatory Response to Hypercapnia Under Propofol Anesthesia

Assessment of Cerebrovascular Autoregulation in Head-Injured Patients: A Validation Study

Analysis of Mean Transit Time of Contrast Medium in Ruptured and Unruptured Arteriovenous Malformations: A Digital Subtraction Angiographic Study

Protein Z in Ischemic Stroke and its Etiologic Subtypes

Effect of Blood Pressure During the Acute Period of Ischemic Stroke on Stroke Outcome: A Tertiary Analysis of the GAIN International Trial

The Cortical Ischemic Core and Not the Consistently Present Penumbra Is a Determinant of Clinical Outcome in Acute Middle Cerebral Artery Occlusion

Editorial Comment—Challenging the Concept of a Dynamic Penumbra in Acute Ischemic Stroke

Comparison of Magnetic Resonance Imaging and Transesophageal Echocardiography in Detection of Thrombus in the Left Atrial Appendage

Prospective Follow-Up Study Between 3 and 15 Months After Stroke: Improvements and Decline in Cognitive Function Among Dementia-Free Stroke Survivors >75 Years of Age

Editorial Comment—Elderly Stroke Patient at Risk for Dementia: In Search of a Profile

Are Patients With Acutely Recovered Cerebral Ischemia More Unstable?

Editorial Comment—Transient Cerebral Ischemia Demands Urgent Evaluation

Prospective Study of Single and Multiple Lacunar Infarcts Using Magnetic Resonance Imaging: Risk Factors, Recurrence, and Outcome in 175 Consecutive Cases

Cerebral Microbleeds as a Risk Factor for Subsequent Intracerebral Hemorrhages Among Patients With Acute Ischemic Stroke

C-Reactive Protein Predicts Further Ischemic Events in First-Ever Transient Ischemic Attack or Stroke Patients With Intracranial Large-Artery Occlusive Disease

Editorial Comment—C-Reactive Protein and Vascular Risk in Stroke Patients: Potential Use for the Future

Greater Impact of Coexistence of Hypertension and Diabetes on Silent Cerebral Infarcts

Physical Activity and Stroke Risk: A Meta-Analysis

Editorial Commen: Physical Exercise and Stroke: The Sitting Majority Has a Lesson to Learn

Hypoxic Induction of Endoglin via Mitogen-Activated Protein Kinases in Mouse Brain Microvascular Endothelial Cells

Glutathione Peroxidase Overexpression Inhibits Cytochrome c Release and Proapoptotic Mediators to Protect Neurons From Experimental Stroke

Mild Hypothermia Inhibits Inflammation After Experimental Stroke and Brain Inflammation

Lifetime Cost of Stroke Subtypes in Australia: Findings From the North East Melbourne Stroke Incidence Study (NEMESIS)

Cost-Effective Outcome for Treating Poor-Grade Subarachnoid Hemorrhage

Research Reports

Remote Evaluation of Acute Ischemic Stroke: Reliability of National Institutes of Health Stroke Scale via Telestroke

Editorial Comment—Remote Evaluation of Acute Ischemic Stroke: A Reliable Tool to Extend Tissue Plasminogen Activator Use to Community and Rural Stroke Patients?

Association Between Interleukin-1A Polymorphism and Cerebral Amyloid Angiopathy–Related Hemorrhage

Comments, Opinions, and Reviews

Human Genome Sequence Variation and the Search for Genes Influencing Stroke

Editorial Comment—The Pendulum’s Swing: The Way Forward in the Genetics of Stroke

Progress Review

Inflammation and Infections as Risk Factors for Ischemic Stroke

Cochrane Corner

Cochrane Stroke Group 10 Years On: Progress to Date and Future Challenges

Letters to the Editor

In Vivo Platelet Activation in Ischemic Stroke Patients • Response

Stroke and HIV Infection • Response

Cerebellar Stroke With Speed-Dependent Gait Ataxia

ASPECTS Reading Requires Training and Experience • Response

Quality of Life During and After Inpatient Stroke Rehabilitation • Response

Potential Value of Triple Antiplatelet Therapy for Secondary Stroke Prevention

ESPRIT: Safety and Efficacy of Oral Anticoagulation—a Rebuttal

Differential Effects of Body Adiposity and Serum Lipids on Right and Left Carotid Artery Lesions • Response

Sex Differences in Carotid Endarterectomy Outcomes • Response

Emerging Therapies

Neurosurgical Clipping Versus Endovascular Coiling of Patients With Ruptured Intracranial Aneurysms

Controversies in Stroke

Measurement of the Ischemic Penumbra With MRI: It’s About Time

Best Measure of Ischemic Penumbra: Positron Emission Tomography

Ischemic Penumbra: MRI or PET

Major Ongoing Stroke Trials