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About This Cover
Volume 38, Issue 10; October 1, 2007
Editorials
Original Contributions
Research Letters
Cochrane Corner
Letters to the Editor
Corrections
Major Ongoing Stroke Trials
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Editorials
Intra-Arterial Fibrinolysis for Acute Ischemic Stroke: The Message of Melt
Jeffrey L. Saver
Stroke. 2007;38:2627-2628; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.490417.
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Do We Need to Assess the Effect of Treatment Withdrawal?: The Paradigm of Life-Long Prevention
François Gueyffier and Théodora Bejan-Angoulvant
Stroke. 2007;38:2629-2630; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.492264.
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To FAST or Not to FAST?
Corinne S. Hodgson
Stroke. 2007;38:2631-2632; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.488809.
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Original Contributions
Randomized Trial of Intraarterial Infusion of Urokinase Within 6 Hours of Middle Cerebral Artery Stroke: The Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial (MELT) Japan
Akira Ogawa, Etsuro Mori, Kazuo Minematsu, Waro Taki, Akira Takahashi, Shigeru Nemoto, Susumu Miyamoto, Makoto Sasaki, Takashi Inoue for The MELT Japan Study Group
Stroke. 2007;38:2633-2639; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.488551.
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MRI-Based and CT-Based Thrombolytic Therapy in Acute Stroke Within and Beyond Established Time Windows: An Analysis of 1210 Patients
Peter D. Schellinger, Götz Thomalla, Jens Fiehler, Martin Köhrmann, Carlos A. Molina, Tobias Neumann-Haefelin, Marc Ribo, Oliver C. Singer, Olivier Zaro-Weber, and Jan Sobesky
Stroke. 2007;38:2640-2645; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.483255.
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Higher Total Serum Cholesterol Levels Are Associated With Less Severe Strokes and Lower All-Cause Mortality: Ten-Year Follow-Up of Ischemic Strokes in the Copenhagen Stroke Study
Tom Skyhøj Olsen, Rune Haubo Bojesen Christensen, Lars Peter Kammersgaard, and Klaus Kaae Andersen
Stroke. 2007;38:2646-2651; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.490292.
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CME
Discontinuation of Statin Therapy and Clinical Outcome After Ischemic Stroke
Furio Colivicchi, Andrea Bassi, Massimo Santini, and Carlo Caltagirone
Stroke. 2007;38:2652-2657; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.487017.
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Recurrent Hemorrhagic Stroke in Children: A Population-Based Cohort Study
Heather J. Fullerton, Yvonne W. Wu, Stephen Sidney, and S. Claiborne Johnston
Stroke. 2007;38:2658-2662; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.481895.
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An Interactive Association of Common Sequence Variants in the Neuropeptide Y Gene With Susceptibility to Ischemic Stroke
Chaeyoung Lee and Minyoung Kong
Stroke. 2007;38:2663-2669; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.482075.
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Association of Kallikrein Gene Polymorphisms With Intracranial Aneurysms
Shantel Weinsheimer, Katrina A.B. Goddard, Antonio R. Parrado, Qing Lu, Moumita Sinha, Elena R. Lebedeva, Antti Ronkainen, Mika Niemelä, Elza K. Khusnutdinova, Rita I. Khusainova, Katariina Helin, Juha E. Jääskeläinen, Vladimir P. Sakovich, Susan Land, Helena Kuivaniemi, and Gerard Tromp
Stroke. 2007;38:2670-2676; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.486225.
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Is There a Direct Link Between Cerebrovascular Activity and Cerebrospinal Fluid Pressure-Volume Compensation?
Christina Haubrich, Zofia Czosnyka, Andrea Lavinio, Piotr Smielewski, Rolf R. Diehl, John D. Pickard, and Marek Czosnyka
Stroke. 2007;38:2677-2680; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.485847.
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Blood Pressure in Relation to the Incidence of Cerebral Infarction and Intracerebral Hemorrhage: Hypertensive Hemorrhage: Debated Nomenclature Is Still Relevant
Elisabet Zia, Bo Hedblad, Hélène Pessah-Rasmussen, Göran Berglund, Lars Janzon, and Gunnar Engström
Stroke. 2007;38:2681-2685; published online before print August 30 2007, doi:10.1161/STROKEAHA.106.479725.
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Echocardiographic Left Ventricular Mass Index Predicts Incident Stroke in African Americans: Atherosclerosis Risk in Communities (ARIC) Study
Ervin R. Fox, Nabhan Alnabhan, Alan D. Penman, Kenneth R. Butler, Herman A. Taylor, Jr, Thomas N. Skelton, and Thomas H. Mosley, Jr
Stroke. 2007;38:2686-2691; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.485425.
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Impaired Endothelial Function of Forearm Resistance Arteries in CADASIL Patients
Anna Stenborg, Hannu Kalimo, Matti Viitanen, Andreas Terent, and Lars Lind
Stroke. 2007;38:2692-2697; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.490029.
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Artery-Related Differences in Atherosclerosis Expression: Implications for Atherogenesis and Dynamics in Intima-Media Thickness
Søren Dalager, William P. Paaske, Ingrid Bayer Kristensen, Jacob Marsvin Laurberg, and Erling Falk
Stroke. 2007;38:2698-2705; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.486480.
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Clinical Diagnosis of Lacunar Stroke in the First 6 Hours After Symptom Onset: Analysis of Data From the Glycine Antagonist In Neuroprotection (GAIN) Americas Trial
Stephen J. Phillips, Dingwei Dai, Arnold Mitnitski, Gordon J. Gubitz, Karen C. Johnston, Walter J. Koroshetz, Karen L. Furie, Sandra Black, Darell E. Heiselman on behalf of the GAIN Americas Investigators
Stroke. 2007;38:2706-2711; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.487744.
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Preoperative Cerebral Hemodynamic Impairment and Reactive Oxygen Species Produced During Carotid Endarterectomy Correlate With Development of Postoperative Cerebral Hyperperfusion
Yasunori Suga, Kuniaki Ogasawara, Hideo Saito, Nobukazu Komoribayashi, Masakazu Kobayashi, Takashi Inoue, Yasunari Otawara, and Akira Ogawa
Stroke. 2007;38:2712-2717; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.483495.
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Risk Factors for Intracerebral Hemorrhage in a Pooled Prospective Study
Jared D. Sturgeon, Aaron R. Folsom, W.T. Longstreth, Jr, Eyal Shahar, Wayne D. Rosamond, and Mary Cushman
Stroke. 2007;38:2718-2725; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.487090.
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Enhanced Detection of Thromboemboli With the Use of Targeted Microbubbles
Matthew J. Martin, Emma M.L. Chung, Alison H. Goodall, Alberto Della Martina, Kumar V. Ramnarine, Lingke Fan, Sarah V. Hainsworth, A. Ross Naylor, and David H. Evans
Stroke. 2007;38:2726-2732; published online before print September 6 2007, doi:10.1161/STROKEAHA.107.489435.
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Iron Oxide Particle-Enhanced MRI Suggests Variability of Brain Inflammation at Early Stages After Ischemic Stroke
Andreas Saleh, Michael Schroeter, Adrian Ringelstein, Hans-Peter Hartung, Mario Siebler, Ulrich Mödder, and Sebastian Jander
Stroke. 2007;38:2733-2737; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.481788.
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B
leeding
R
isk
A
nalysis in
S
troke
I
maging Before Thrombo
L
ysis (BRASIL): Pooled Analysis of T2*-Weighted Magnetic Resonance Imaging Data From 570 Patients
Jens Fiehler, Gregory W. Albers, Jean-Martin Boulanger, Laurent Derex, Achim Gass, Niels Hjort, Jong S. Kim, David S. Liebeskind, Tobias Neumann-Haefelin, Salvador Pedraza, Joachim Rother, Peter Rothwell, Alex Rovira, Peter D. Schellinger, Johannes Trenkler for the MR STROKE Group
Stroke. 2007;38:2738-2744; published online before print August 23 2007, doi:10.1161/STROKEAHA.106.480848.
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Urinary Incontinence After Stroke: Identification, Assessment, and Intervention by Rehabilitation Professionals in Canada
Chantale Dumoulin, Nicol Korner-Bitensky, and Cara Tannenbaum
Stroke. 2007;38:2745-2751; published online before print September 6 2007, doi:10.1161/STROKEAHA.107.486035.
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Treadmill Aerobic Training Improves Glucose Tolerance and Indices of Insulin Sensitivity in Disabled Stroke Survivors: A Preliminary Report
Frederick M. Ivey, Alice S. Ryan, Charlene E. Hafer-Macko, Andrew P. Goldberg, and Richard F. Macko
Stroke. 2007;38:2752-2758; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.490391.
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The Increase of Circulating Endothelial Progenitor Cells After Acute Ischemic Stroke Is Associated With Good Outcome
Tomás Sobrino, Olivia Hurtado, María Ángeles Moro, Manuel Rodríguez-Yáñez, Mar Castellanos, David Brea, Octavio Moldes, Miguel Blanco, Juan F. Arenillas, Rogelio Leira, Antonio Dávalos, Ignacio Lizasoain, and José Castillo
Stroke. 2007;38:2759-2764; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.484386.
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The Impact of Ambulance Practice on Acute Stroke Care
Ian Mosley, Marcus Nicol, Geoffrey Donnan, Ian Patrick, Fergus Kerr, and Helen Dewey
Stroke. 2007;38:2765-2770; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.483446.
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Mouse Model of In Situ Thromboembolic Stroke and Reperfusion
Cyrille Orset, Richard Macrez, Alan R. Young, Didier Panthou, Eduardo Angles-Cano, Eric Maubert, Veronique Agin, and Denis Vivien
Stroke. 2007;38:2771-2778; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.487520.
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Stimulating Circle of Willis Nerve Fibers Preserves the Diffusion-Perfusion Mismatch in Experimental Stroke
Nils Henninger and Marc Fisher
Stroke. 2007;38:2779-2786; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.485581.
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Molecular Indices of Apoptosis Activation in Elastase-Induced Aneurysms After Embolization With Platinum Coils
Ramanathan Kadirvel, Yong-Hong Ding, Daying Dai, Debra A. Lewis, Harry J. Cloft, and David F. Kallmes
Stroke. 2007;38:2787-2794; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.486738.
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Erythropoietin Promotes Neuronal Replacement Through Revascularization and Neurogenesis After Neonatal Hypoxia/Ischemia in Rats
Masanori Iwai, Guodong Cao, Wei Yin, R. Anne Stetler, Jialing Liu, and Jun Chen
Stroke. 2007;38:2795-2803; published online before print August 16 2007, doi:10.1161/STROKEAHA.107.483008.
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Beneficial Effects of Hematopoietic Growth Factor Therapy in Chronic Ischemic Stroke in Rats
Li-Ru Zhao, Hector H. Berra, Wei-Ming Duan, Seema Singhal, Jayesh Mehta, A. Vania Apkarian, and John A. Kessler
Stroke. 2007;38:2804-2811; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.486217.
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Lipopolysaccharide Induces Early Tolerance to Excitotoxicity via Nitric Oxide and cGMP
Marcello Orio, Alexander Kunz, Takayuki Kawano, Josef Anrather, Ping Zhou, and Costantino Iadecola
Stroke. 2007;38:2812-2817; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.486837.
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Continuous Time-Domain Analysis of Cerebrovascular Autoregulation Using Near-Infrared Spectroscopy
Ken M. Brady, Jennifer K. Lee, Kathleen K. Kibler, Piotr Smielewski, Marek Czosnyka, R. Blaine Easley, Raymond C. Koehler, and Donald H. Shaffner
Stroke. 2007;38:2818-2825; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.485706.
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Selective Impairment of Working Memory in a Mouse Model of Chronic Cerebral Hypoperfusion
Masunari Shibata, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Rajesh N. Kalaria, Youshi Fujita, Ryo Ohtani, Masafumi Ihara, Ryosuke Takahashi, and Hidekazu Tomimoto
Stroke. 2007;38:2826-2832; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.490151.
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Effects of Skilled Forelimb Training on Hippocampal Neurogenesis and Spatial Learning After Focal Cortical Infarcts in the Adult Rat Brain
Fanny Wurm, Silke Keiner, Albrecht Kunze, Otto W. Witte, and Christoph Redecker
Stroke. 2007;38:2833-2840; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.485524.
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Data Supplement
Research Letters
Detection of Carotid Adventitial Vasa Vasorum and Plaque Vascularization With Ultrasound Cadence Contrast Pulse Sequencing Technique and Echo-Contrast Agent
Edoardo Vicenzini, Maria Fabrizia Giannoni, Francesco Puccinelli, Maria Chiara Ricciardi, Marta Altieri, Vittorio Di Piero, Bruno Gossetti, Fabrizio Benedetti Valentini, and Gian Luigi Lenzi
Stroke. 2007;38:2841-2843; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.487918.
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Data Supplement
Leptin:Adiponectin Ratio Is an Independent Predictor of Intima Media Thickness of the Common Carotid Artery
Giuseppe Danilo Norata, Sara Raselli, Liliana Grigore, Katia Garlaschelli, Elena Dozio, Paolo Magni, and Alberico L. Catapano
Stroke. 2007;38:2844-2846; published online before print September 6 2007, doi:10.1161/STROKEAHA.107.485540.
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Association of the Glutathione S-transferase Omega-1 Ala140Asp Polymorphism With Cerebrovascular Atherosclerosis and Plaque-Associated Interleukin-1
Expression
Heike Kölsch, Sergey Larionov, Oliver Dedeck, Mario Orantes, Gerd Birkenmeier, W. Sue T. Griffin, and Dietmar Rudolf Thal
Stroke. 2007;38:2847-2850; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.484162.
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Magnetic Resonance Spectroscopy Study of Oxygen Therapy in Ischemic Stroke
Aneesh B. Singhal, Eva Ratai, Thomas Benner, Mark Vangel, Vallent Lee, Walter J. Koroshetz, Pamela W. Schaefer, A. Gregory Sorensen, and R. Gilberto Gonzalez
Stroke. 2007;38:2851-2854; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.487280.
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Endovascular Occlusion of Aneurysms Using a New Bioactive Coil: A Matched Pair Analysis With Bare Platinum Coils
Martin Bendszus, Andreas J. Bartsch, and Laszlo Solymosi
Stroke. 2007;38:2855-2857; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.489088.
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The Met Allele of the BDNF Val66Met Polymorphism Predicts Poor Outcome Among Survivors of Aneurysmal Subarachnoid Hemorrhage
Jari Siironen, Seppo Juvela, Katarzyna Kanarek, Juhani Vilkki, Juha Hernesniemi, and Jaakko Lappalainen
Stroke. 2007;38:2858-2860; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.485441.
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A New Hippocampal Model for Examining Intracerebral Hemorrhage-Related Neuronal Death: Effects of Deferoxamine on Hemoglobin-Induced Neuronal Death
Shuijiang Song, Ya Hua, Richard F. Keep, Julian T. Hoff, and Guohua Xi
Stroke. 2007;38:2861-2863; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.488015.
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Designing a Message for Public Education Regarding Stroke: Does FAST Capture Enough Stroke?
Dawn O. Kleindorfer, Rosie Miller, Charles J. Moomaw, Kathleen Alwell, Joseph P. Broderick, Jane Khoury, Daniel Woo, Matthew L. Flaherty, Tarek Zakaria, and Brett M. Kissela
Stroke. 2007;38:2864-2868; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.484329.
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Cochrane Corner
Rehabilitation for Spatial Neglect Improves Test Performance but Not Disability
Audrey Bowen and Nadina B. Lincoln
Stroke. 2007;38:2869-2870; published online before print August 30 2007, doi:10.1161/STROKEAHA.107.490227.
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Letters to the Editor
Overestimation of Coronary Risk in Stroke Patients
Emmanuel Touzé, Olivier Varenne, and Jean-Louis Mas
Stroke. 2007;38:e98; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.491258.
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Response to Letter by Touzé et al
Mandip S. Dhamoon and Mitchell S.V. Elkind
Stroke. 2007;38:e99; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.494609.
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Comparison of the Carotid Stenosis Index With CT Angiography
Christopher Bladin, Andrei V. Alexandrov, and John Norris
Stroke. 2007;38:e100-e101; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.489260.
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Response to Letter by Bladin et al
Eric S. Bartlett, Thomas D. Walters, Sean P. Symons, and Allan J. Fox
Stroke. 2007;38:e102; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.493072.
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Recanalization Rates Can Be Misleading
Thomas A. Kent and Pitchaiah Mandava
Stroke. 2007;38:e103; published online before print September 6 2007, doi:10.1161/STROKEAHA.107.492405.
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Response to Letter by Kent and Mandava
Joung-Ho Rha and Jeffrey L. Saver
Stroke. 2007;38:e104; published online before print September 6 2007, doi:10.1161/STROKEAHA.107.494484.
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"Prevention": the Right Term?
R. Sivakumar
Stroke. 2007;38:e105; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.492389.
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Stroke in Diabetic Patients: Is It Really a Macrovascular Complication?
Luis Castilla-Guerra and Maria del Carmen Fernandez-Moreno
Stroke. 2007;38:e106; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.492843.
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Combining Antiplatelet Drugs and Oral Anticoagulant Therapy in Atrial Fibrillation: Acute Coronary Syndromes and/or Percutaneous Coronary Intervention/Stenting Revisited
Timothy Watson and Gregory Y.H. Lip
Stroke. 2007;38:e107-e108; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.492488.
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SAINT-I Worked, But the Neuroprotectant Is Not NXY-059
Peter H. Proctor and Lynsey P. Tamborello
Stroke. 2007;38:e109; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.489161.
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Response to Letter by Proctor and Tamborello
Kennedy R. Lees, Tim Ashwood, and Tomas Odergren
Stroke. 2007;38:e110; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.493411.
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Two Common Gene Variants on Chromosome 9 and Risk of Atherothrombosis
Robert Y.L. Zee and Paul M Ridker
Stroke. 2007;38:e111; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.497669.
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Higher Stroke Mortality on Weekends: Are All Strokes the Same?
Roberto Manfredini, Benedetta Boari, and Raffaella Salmi
Stroke. 2007;38:e112; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.489898.
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Rigorously Investigating the Weekend Effect on Short-Term Mortality for Patients Admitted With Stroke
Cody Hamilton and Giovanni Filardo
Stroke. 2007;38:e113; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.488924.
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Response to Letters by Hamilton and Filardo, and Manfredini et al
Gustavo Saposnik, Neville Bayer, and Vladimir Hachinski
Stroke. 2007;38:e114; published online before print August 23 2007, doi:10.1161/STROKEAHA.107.491076.
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Corrections
Correction
Stroke. 2007;38:e115, doi:10.1161/STROKEAHA.106.222111.
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Major Ongoing Stroke Trials
Major Ongoing Stroke Trials
Stroke. 2007;38:e116-e125, doi:10.1161/STROKEAHA.107.111222.
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