Table 11.

Additional Inclusion and Exclusion Characteristics of Patients With Acute Ischemic Stroke Who Could Be Treated With IV rtPA Within 3 to 4.5 Hours From Symptom Onset

Inclusion criteria
  Diagnosis of ischemic stroke causing measurable neurological deficit
  Onset of symptoms within 3 to 4.5 hours before beginning treatment
Relative exclusion criteria
  Aged >80 years
  Severe stroke (NIHSS>25)
  Taking an oral anticoagulant regardless of INR
  History of both diabetes and prior ischemic stroke
  • INR indicates international normalized ratio; IV, intravenous; NIHSS, National Institutes of Health Stroke Scale; and rtPA, recombinant tissue plasminogen activator.