Table 3.

Comparison Between Patients With Good and Poor Outcomes

Derivation Cohort (n=83)Validation Cohort (n=41)
Good Outcome (n=34)Poor Outcome (n=49)P ValueGood Outcome (n=20)Poor Outcome (n=21)P Value
Age (y), mean61±1769±120.0159±1765±140.3
NIHSS, median (IQR)8 (3–15)22 (8–28)0.00410 (4–19)20 (11–33)0.02
Coma, n (%)5 (15)24 (49)0.0023 (15)9 (43)0.08
Male sex, n (%)21 (62)37 (75.5)0.211 (55)16 (76)0.2
Risk factors, n (%)
 Hypertension14 (41)25 (51)0.911 (55)11 (52)0.9
 Hypercholesterolemia8 (23.5)16 (33)0.65 (25)4 (19)0.5
 Diabetes mellitus3 (9)18 (37)0.0054 (20)7 (33)0.5
 Atrial fibrillation10 (29)15 (31)0.93 (15)5 (24)0.7
 Smoking9 (26.5)8 (16)0.36 (30)7 (33)0.9
 Coronary artery disease8 (23.5)14 (29)0.82 (10)3 (14)0.9
  Previous TIA/stroke2 (6)5 (10)0.72 (10)3 (14)0.9
Stroke cause, n (%)*
 Cardioembolic9 (26.5)13 (26.5)0.95 (25)6 (29)0.9
 Atherosclerotic6 (18)13 (26.5)0.45 (25)11 (52)0.07
 Other3 (9)15(31)0.032 (10)00.2
 Undetermined11 (32)13 (26.5)0.67 (35)5 (24)0.5
Intravenous thrombolysis, n (%)11 (32)15 (31)0.916 (80)16 (76)0.9
Endovascular treatment, n (%)25 (73.5)31 (63)0.37 (35)10 (48)0.5
Heparin infusion, n (%)6 (18)3 (6)0.1
Location of the occlusion, n (%)
 Proximal basilar artery9 (26.5)18 (37)0.38 (40)6 (29)0.5
 Middle basilar artery14 (41)30 (61)0.084 (20)9 (43)0.2
 Distal basilar artery23 (68)33 (67)0.911 (55)14 (67)0.5
 Posterior cerebral arteries12 (35)33 (67)0.0076 (30)11 (52)0.2
 Vertebral arteries12 (35)22 (45)0.53 (15)6 (29)0.4
 Absence of PComs8 (23.5)30 (61)0.00110 (50)12 (57)0.7
BATMAN score, median (IQR)7 (6–8)5 (3–6)<0.0017 (6–8)6 (5–6)0.004
pc-CTA score, median (IQR)2 (2–3)3 (2–4)0.021 (1–2)3 (1–3)0.01
PC-CS score, median (IQR)6 (4–8)4 (3–6)0.035 (4–7)5 (4–6)0.3
  • BATMAN indicates Basilar artery on Tomography Angiography; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; PC-CS, Posterior Circulation Collateral score; pc-CTA, posterior circulation computed tomographic angiography; PCom, posterior communicating artery; and TIA, transient ischemic attack.

  • * Trial of Org 10172 in Acute Stroke Treatment classification.