Table 2.

Baseline Characteristics in Derivation Cohort and Validation Cohort

Derivation Cohort (n=83)Validation Cohort (n=41)P Value
 Age (y), mean66±1562±160.2
 NIHSS, median (IQR)16 (6–28)17 (7–29)0.7
 Coma, n (%)29 (35)12 (29)0.5
 Male sex, n (%)58 (70)27 (66)0.7
Risk factors, n (%)
 Hypertension39 (47)22 (54)0.6
 Hypercholesterolemia24 (29)9 (22)0.5
 Diabetes mellitus21 (25)11 (27)0.9
 Atrial fibrillation25 (30)8 (19.5)0.3
 Smoking17 (20.5)13 (32)0.2
 Coronary artery disease22 (26.5)5 (12)0.1
 Previous TIA/stroke7 (8.5)5 (12)0.5
Stroke cause, n (%)*
 Cardioembolic22 (26.5)11 (27)0.9
 Atherosclerotic19 (23)16 (39)0.1
 Other14 (17)2 (5)0.1
 Undetermined28 (34)12 (29)0.7
Intravenous thrombolysis, n (%)26 (31)32 (78)<0.001
Endovascular treatment, n (%)56 (67.5)17 (41.5)0.007
Heparin infusion, n (%)9 (11%)00.03
Location of the occlusion, n (%)
 Proximal basilar artery27 (32.5)14 (34)0.9
 Middle basilar artery44 (53)14 (34)0.06
 Distal basilar artery56 (67.5)25 (61)0.5
 Posterior cerebral arteries45 (54)17 (41.5)0.2
 Vertebral arteries34 (41)9 (22)0.2
 Absence of PComs38 (46)22 (54)0.4
BATMAN score, median (IQR)6 (4–7)6 (5–7)0.1
pc-CTA score, median (IQR)3 (2–4)2 (1–3)0.01
PC-CS score, median (IQR)5 (4–7)5 (4–6)0.1
  • Note: 3 patients did not receive treatment because of extensive early ischemic changes on admission noncontrast computed tomography. BATMAN indicates Basilar Artery on Tomography Angiography; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; PC-CS, Posterior Circulation Collateral score; pc-CTA, posterior circulation computed tomographic angiography; PCom, posterior communicating artery; and TIA, transient ischemic attack.

  • * Trial of Org 10172 in Acute Stroke Treatment classification.